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. 2018 Nov 8;13:7289–7302. doi: 10.2147/IJN.S175334

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© 2018 Li et al. This work is published and licensed by Dove Medical Press Limited

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Scratch test and anti-angiogenesis effect in vitro.

Notes: (A) Representative images of the scratch test after co-incubation of HUVECs with CuS NPs, CuS NPs + Ab and CuS-Ab NPs; control group: without treatment (magnification: 40× objective). (B) Semi-quantitative analysis of percentage migration. (C) Blood density of ECM after 1 week of treatment. (D) Semi-quantitative analysis of vessel density in ECM. *P<0.05, **P<0.01.

Abbreviations: CuS NP, CuS nanoparticle; CuS-Ab NP, cetuximab-modified CuS NP; ECM, embryo chorioallantoic membrane; HUVEC, human umbilical vein endothelial cell.