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Kinetic behavior of blood biomarkers is predicted in part by their molecular weight and rate of glomerular filtration.
Notes: (A) Biomarkers levels in serum. (B) Time course of biomarker levels after BBBD, measured in serum. (C) Urine levels of biomarkers due to glomelural filtration. Note that the marker with higher m.w., GFAP, is retained in blood longer (B) and appears in urine (C) with a delay.
Abbreviation: GFAP, glial fibrillary acidic protein.
