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. 2018 Nov 8;13:7251–7273. doi: 10.2147/IJN.S173198

Figure 6.

Figure 6

NPs retention on ocular surface.

Notes: (A) Accumulation of fluorescent particles on rat eye after 5 minutes’ dosing with different formulations. (B) Retention of fluorescent particles on the ocular surface traced by in vivo imaging system at different time intervals. The GEH group displayed markedly more fluorescent spots on the ocular surface. Colored photographs showing ocular retention of the dye/drug in rats treated with eye drops containing EGCG solution, GE, or GEH. A fluorescent dye (tetramethylrhodamine, 0.5 µg/mL) was added to all solutions for fluorescence staining.

Abbreviations: EGCG, epigallocatechin gallate; GE, gelatin–EGCG; GEH, GE with hyaluronic acid coating; NPs, nanoparticles.