Table 2.
Quantification of DA and NA in brain areas involved during the MGT
| ASD | DA | NA | ||||
|---|---|---|---|---|---|---|
| Control | P value | ASD | Control | P value | ||
| OFC | 1819 ± 53.7 | 1799 ± 82.3 | p = 0.85 | 1409 ± 58.7 | 1499 ± 90.4 | p = 0.46 |
| PrL/IL | 2302 ± 68.2 | 2089 ± 100.1 | p = 0.15 | 1327 ± 38.9 | 1209 ± 71.8 | p = 0.16 |
| Cins | 1993 ± 46.7 | 1711 ± 67.9 | *p = 0.01 | 1282 ± 57 | 1129 ± 106.9 | p = 0.22 |
| Amy | 9737 ± 402.2 | 9818 ± 1154.3 | p = 0.93 | 7314 ± 409.8 | 6577 ± 37.6 | p = 0.38 |
| Hippocampus | 1853 ± 45.5 | 1914 ± 177.1 | p = 0.59 | 1915 ± 61 | 1873 ± 67.1 | p = 0.74 |
| CPu | 72790 ± 2280.9 | 59082 ± 1434.9 | *p = 0.01 | 4226 ± 205.3 | 384.4 ± 95.1 | p = 0.39 |
| *p < 0.05 | ||||||
DA and NA levels (mean ± SEM) in the OFC, Pre and Infra limbic (PrL/IL), CIns, Amy, hippocampus, and CPu for control animals (n = 3) and sleep debt animals (ASD, n = 12, *p < 0.05). ASD animals also exhibited higher DA in the CIns and the CPu (*p <0.05 in bold).