Table 3. List of positively selected genes in Corynebacterium pseudotuberculosis in different branches (FDR < 0.05).
| GenBank ID (Equi/ Ovis) |
1 | 2 | 3 | 4 | 5 | 7 | 8 | Product (Gene) | Function | PAI | Reference (Drug target or Vaccine) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cp31_0488/ Cp1002B_0499 | X | Drug resistance transporter | Resistance | - | [62,63] | ||||||
| Cp31_1168/ Cp1002B_1500 | X | Citrate lyase beta chain (citE) | Metabolism | - | [64] | ||||||
| Cp31_1468/ Cp1002B_1186 | X | Cell-surface hemin receptor (hatF) | Transport | PiCp5 | - | ||||||
| Cp31_2169/ Cp1002B_0189 | X | Hypothetical protein 1 (no domains) | Unknown | PiCp3 | - | ||||||
| Cp31_0206/ Cp1002B_0207 | X | X | Sialidase 1 | Virulence | PiCp13 | [65,66] | |||||
| Cp31_0638/ Cp1002B_2037 | X | Dihydrofolate reductase (folA) | Metabolism | - | [67] | ||||||
| Cp31_0945/ Cp1002B_1731 | X | Coenzyme PQQ biosynthesis protein E (pqqE) | Metabolism | - | - | ||||||
| Cp31_0950/ Cp1002B_1726 | X | Metallo-beta-lactamase | Resistance | - | [68] | ||||||
| Cp31_0985/ Cp1002B_1689 | X | Dethiobiotin synthetase (bioD) | Metabolism | - | [69,70] | ||||||
| Cp31_1044/ Cp1002B_1624 | X | Pup deaminase (dop) | Metabolism | - | [71,72] | ||||||
| Cp31_1309/ Cp1002B_1363 | X | X | X | X | Cobalt chelatase subunit CobS (cobS) | Metabolism | - | - | |||
| Cp31_1724/ Cp1002B_0908 | X | X | X | X | Hypothetical protein 3 (no domains) | Unknown | - | - | |||
| Cp31_1868/ Cp1002B_0763 | X | Membrane anchored protein 1 | Unknown | PiCp13 | - | ||||||
| Cp31_0109/ Cp1002B_0104 | X | Alpha / beta hydrolase | Unknown | - | [73] | ||||||
| Cp31_2015/ Cp1002B_2083 | X | Transmembrane protein | Unknown | PiCp16 | - | ||||||
| Cp31_2279/ - | X | X | Adhesin 1 (membrane anchored) | Adhesion | - | - | |||||
| Cp31_0366/ Cp1002B_0381 | X | Hypothetical protein 2 (no domains) | Unknown | - | - | ||||||
| Cp31_1094/ Cp1002B_1575 | X | Adhesin 2 (membrane anchored) | Adhesion | - | - | ||||||
| Cp31_1977/ Cp1002B_0655 | X | Membrane anchored protein 2 | Unknown | - | - | ||||||
| Cp31_0279/ Cp1002B_0289 | X | Glutamyl-tRNA reductase (hemA) | Metabolism | - | [74] | ||||||
| Cp31_1028/ Cp1002B_1640 | X | Cobaltochelatase subunit CobN (cobN) | Metabolism | - | - | ||||||
| Cp31_1117/ Cp1002B_1551 | X | Sporulation regulator WhiA-like (whiA) | Cell division | - | - | ||||||
| Cp31_0142/ Cp1002B_0139 | X | X | Secreted protein | Unknown | PiCp12 | - | |||||
| Cp31_0180/ Cp1002B_0178 | X | X | Adhesin 3 (thioester domain) | Adhesion | PiCp8 | - | |||||
| Cp31_0399/ Cp1002B_0408 | X | X | Sialidase 2 (nanH) | Metabolism | - | [65,66] | |||||
| Cp31_0893/ Cp1002B_1784 | X | X | Lysine exporter protein (lysE) | Transport | - | [75] | |||||
| Cp31_2281/ Cp1002B_0835 | X | Hypothetical protein 4 (no domains) | Unknown | - |
PAI–Pathogenicity island