Table 5.
Cost-effectiveness analyses and sensitivity analyses for rate of responders to treatment and quality-adjusted life-years (QALYs) at 3-month follow-up.
| Analysis | Incremental cost (€) | Incremental effect | Mean ICERa | Distribution of 5000 bootstrap simulated ICERs | ||||
| NEb | SEc (dominant) | SWd | NWe (inferior) | |||||
| Cost effectiveness, rate of responders to treatment | ||||||||
|
|
Main analysis | –225 | 0.07 | Dominant | 25.2 | 72.4 | 1.6 | 0.8 |
|
|
Only including participants with paid job | –309 | 0.12 | Dominant | 25.0 | 74.6 | 0.3 | 0.1 |
|
|
Analysis without baseline adjustments | –131 | 0.07 | Dominant | 33.7 | 63.9 | 1.4 | 1.0 |
|
|
Health care perspective | –78 | 0.07 | Dominant | 17.1 | 80.5 | 1.9 | 0.5 |
|
|
Including opportunity costs for participants | –225 | 0.07 | Dominant | 25.2 | 72.4 | 1.6 | 0.8 |
|
|
Regression-based imputation | –127 | 0.07 | Dominant | 34.4 | 63.3 | 1.3 | 1.0 |
|
|
Last observation carried forward | –784 | 0.05 | Dominant | 4.5 | 90.5 | 4.7 | 0.3 |
| Cost utility, QALYs | ||||||||
|
|
Main analysis | –225 | 0.12 | Dominant | 24.7 | 75.3 | 0 | 0 |
|
|
Only including participants with paid job | –312 | 0.15 | Dominant | 24.9 | 75.1 | 0 | 0 |
|
|
Analysis without baseline adjustments | –131 | 0.12 | Dominant | 34.7 | 65.3 | 0 | 0 |
|
|
Health care perspective | –85 | 0.12 | Dominant | 16.1 | 83.9 | 0 | 0 |
|
|
Including opportunity costs for participants | –228 | 0.12 | Dominant | 25.7 | 74.3 | 0 | 0 |
|
|
Regression-based imputation | –130 | 0.12 | Dominant | 35.1 | 64.9 | 0 | 0 |
|
|
Last observation carried forward | –785 | 0.06 | Dominant | 4.8 | 95.0 | 0.2 | 0.1 |
aICER: incremental cost-effectiveness ratio.
bNE: northeast quadrant (the intervention was more effective and more costly than usual care).
cSE: southeast quadrant (the intervention was more effective and less costly than usual care).
dSW: southwest quadrant (the intervention was less effective and less costly than usual care).
eNW: northwest quadrant (the intervention was less effective and more costly than usual care).