Table 3.
Univariate Odds Ratios (ORs) for Left Ventricular Hypertrophy (LVH) and Diastolic Dysfunction (DD)
Variable | LVH (n = 448) |
DD (n = 224) |
||||
---|---|---|---|---|---|---|
OR | 95% CI | P value | OR | 95% CI | P value | |
Age, per 10-y increase | 1.10 | 0.92—1.31 | .30 | 1.37 | 1.06—1.76 | .01 |
Black race | 1.22 | 0.79—1.88 | .38 | 0.76 | 0.43—1.36 | .35 |
Hypertension | 1.56 | 1.05—2.31 | .03 | 1.21 | 0.71—2.05 | .48 |
Hyperlipidemia | 1.22 | 0.75—2.00 | .42 | 1.43 | 0.77—2.66 | .25 |
Diabetes mellitus | 1.33 | 0.83—2.16 | .23 | 1.79 | 0.94—3.44 | .08 |
Cocaine use | 1.45 | 0.97—2.17 | .07 | 0.88 | 0.50—1.54 | .65 |
Tobacco use, current | 1.25 | 0.75—2.10 | .37 | 0.49 | 0.29—0.84 | .01 |
Tobacco use, any | 1.19 | 0.81—1.76 | .39 | 1.40 | 0.66—2.96 | .38 |
Hepatitis C infection | 0.92 | 0.56—1.52 | .75 | 0.93 | 0.48—1.79 | .82 |
Time from HIV diagnosis to first TTE, per 5-y increase | 0.99 | 0.85—1.16 | .90 | 1.07 | 0.87—1.31 | .53 |
ACE inhibitor use | 1.44 | 0.91—2.27 | .12 | 1.30 | 0.72—2.37 | .38 |
Beta-blocker use | 1.76 | 1.10—2.82 | .02 | 2.01 | 1.09—3.71 | .03 |
Abacavir exposure | 0.73 | 0.44—1.21 | .22 | 0.86 | 0.46—1.62 | .64 |
Didanosine/stavudine exposure | 1.05 | 0.68—1.63 | .82 | 1.30 | 0.69—2.44 | .42 |
Zidovudine exposure | 1.10 | 0.73 — 1.67 | .89 | 0.64 | 0.36—1.15 | .33 |
PI exposure | 0.87 | 0.59—1.28 | .48 | 0.85 | 0.50—1.44 | .54 |
ACE, angiotensin-converting enzyme inhibitor; CI, confidence interval; PI, protease inhibitor.