Table 5.

Univariate and Multivariate Associations of Clinical Variables with HOMA-IR.

Measure	HOMA-IR
	Univariate model			Multivariate model
				Model 1			Model 2			Model 3
	β	p		β	p		β	p		β	p
Sex (female)				0.087	0.1935		0.100	0.14		0.107	0.11
Age	-0.092	0.270		0.163	0.0615		0.155	0.09		0.136	0.12
BMI	0.349	<0.0001		0.217	0.0033		0.223	0.0032		0.234	0.0016
eGFR	0.079	0.290		0.034	0.67		0.045	0.58		0.049	0.535
ALT	0.448	<0.0001		0.334	<0.0001		0.352	<0.0001		0.342	<0.0001
TGL	0.235	0.0013		0.112	0.10		0.154	0.03		0.158	0.02
HbA1c	-0.099	0.18		-0.001	0.98		-0.030	0.66		-0.001	0.99
DGLA	0.349	<0.0001		0.195	0.0066
AA	0.221	0.0026					0.065	0.38
Estimated D5D	-0.216	0.0032								-0.147	0.024
R2	-			0.3219			0.296			0.313
p	-			<0.0001			<0.0001			<0.0001

ρ: Spearman correlation coefficient, β: standard partial regression coefficient. HOMA-IR: homeostatic model assessment of insulin resistance, BMI: body mass index, eGFR: estimated glomerular filtration rate, ALT: alanine amino transferase, TGL: triglyceride, HbA1c: glycated hemoglobin, DGLA: dihomo-γ-linolenic acid, AA: arachidonic acid, D5D: Δ-5 desaturase