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. 2018 Nov 6;9:1219. doi: 10.3389/fphar.2018.01219

Table 5.

% fenofibrate in aqueous phase (AP) and pellet phase (PP) after 30 min digestion under fed and fasted condition, (n = 3 ± SD).

No. Formulation Fasted
Fed
% Drug in AP % Drug in PP %Tot. Rec. % Drug in AP % Drug in PP %Tot. Rec.
F2a C70:CMCM(7:3)/TO106V (1/1) 9.22 ± 0.67 79.23 ± 1.23 88.45 8.99 ± 1.11 78.99 ± 0.77 87.98
F2b K70:I742(7:3)/To-106V(1/1) 11.23 ± 3.23 84.79 ± 0.87 96.02 10.09 ± 0.21 83.36 ± 1.07 93.45
F3a C70:CMCM(7:3)/ HCO-30 (1/1) 08.24 ± 0.00 78.72 ± 0.20 86.96 07.20 ± 0.61 85.44 ± 0.02 92.64
F3b K70:I742(7:3)/HCO-30 (1/1) 10.18 ± 0.00 83.41 ± 0.80 93.59 4.84 ± 0.00 88.68 ± 1.11 93.52
F4a CMCM/HCO-30 (1/1) 7.64 ± 2.11 84.81 ± 0.44 92.45 7.43 ± 1.32 84.23 ± 3.11 91.66
F4b I742/ HCO-30 (1/1) 9.79 ± 0.03 86.75 ± 0.00 96.54 8.75 ± 0.50 85.29 ± 0.93 92.04

Concentration of fenofibrate (mg) in mixed BS micelles before and after digestion under fed conditions. The data represent the original mass of fenofibrate which was recovered from the aqueous and pellet phases after digestion.