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. 2018 Nov 12;8:16711. doi: 10.1038/s41598-018-34652-9

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison between reconstructions of raw and enhanced data. (A) The 3D reconstruction of ModB₂C₂ by back projection from tilt images set at SNR = 0.80, 0.50, and 0.30. The first row is the representative image of projections (at 0^° tilt). The second row is the 3D reconstructions from raw data (left) and enhanced data (right) (both maps were low-pass filterred to ~8 Å). The third row is the FSC curves of the 3D reconstructions using raw and enhanced data. (B) The 3D reconstruction of CETP at SNR = 0.80, 0.50, and 0.30 respectively. Scale bars are 5 nm.