Table 1.
Demographic and clinical data of study participants.
| Blended n = 261 | NERD n = 108 | NIUA n = 511 | p-value Blended vs NERD vs NIUA | p-value Blended vs NERD | p-value Blended vs NIUA | p-value NERD vs NIUA | |
|---|---|---|---|---|---|---|---|
| Age median (IQR) | 37 (29–48) | 39 (30–48.5) | 38 (28–50.7) | NS | NS | NS | NS |
| Gender (female), n (%) | 176 (67.4) | 73 (67.6) | 296 (58) | 0.03 | NS | 0.01 | 0.01 |
| Underlying rhinitis, n (%) | 158 (60.5) | 77 (71.3) | 185 (36.2) | <0.0001 | NS | 0.0002 | <0.0001 |
| Underlying asthma, n (%) | 123 (47.1) | 70 (64.8) | 98 (19.2) | <0.0001 | <0.0001 | <0.0001 | <0.0001 |
| Nasosinusal polyposis, n (%) | 24 (9.2) | 42 (38.9) | 0 | <0.0001 | <0.0001 | <0.0001 | <0.0001 |
| Food allergy, n (%) | 0 | 0 | 15 (3) | 0.004 | NS | 0.005 | NS |
| Atopy, n (%) | 187 (71.6) | 59 (54.6) | 335 (65.5) | NS | 0.002 | NS | NS |
| Positive to at least one inhalant allergen, n (%) | 181 (69.3) | 59 (54.6) | 328 (64.2) | NS | NS | NS | NS |
| Lolium; | 91 (34.9) | 19 (17.6) | 82 (16) | 0.001 | 0.03 | 0.0002 | NS |
| Cupressus; | 28 (10.7) | 1 (0.9) | 48 (9.4) | 0.014 | 0.002 | NS | 0.005 |
| Olea; | 98 (37.5) | 19 (17.6) | 159 (31.1) | 0.004 | NS | NS | 0.02 |
| Parietaria; | 19 (7.3) | 9 (8.3) | 30 (5.9) | NS | NS | NS | NS |
| Salsola; | 22 (8.4) | 2 (1.8) | 40 (7.8) | NS | NS | NS | NS |
| D. pteronyssinuss; | 108 (41.4) | 32 (29.6) | 219 (42.8) | NS | NS | NS | NS |
| Alternaria; | 46 (17.6) | 6 (5.5) | 37 (7.2) | 0.016 | 0.02 | 0.008 | NS |
| Dog dander; | 76 (29.1) | 12 (11.1) | 73 (14.3) | 0.003 | 0.005 | 0.002 | NS |
| Cat dander; | 67 (25.7) | 13 (12) | 88 (17.2) | NS | 0.03 | NS | NS |
| Positive to at least one food allergen, n (%) | 81 (31) | 32 (29.6) | 83 (16.2) | NS | NS | NS | 0.02 |
| Pru p 3 | 28 (10.7) | 0 | 26 (5.1) | 0.0001 | 0.0003 | NS | 0.01 |
| Apple | 24 (9.2) | 0 | 10 (3.8) | <0.0001 | 0.001 | NS | NS |
| Peanut | 49 (18.7) | 15 (13.9) | 14 (2.7) | 0.03 | NS | 0.04 | NS |
| Walzetnut | 49 (18.7) | 15 (13.9) | 15 (2.9) | 0.03 | NS | 0.04 | NS |
| Melon | 23 (8.8) | 0 | 22 (4.3) | 0.0009 | 0.001 | NS | 0.02 |
| Shrimp | 29 (11.1) | 10 (9.2) | 14 (2.7) | 0.01 | NS | 0.04 | 0.04 |
IQR: interquartile range; NS: Not significant.