Table 2.
Average ranking of identified pathogenic genes in each method.
| Methods | 1% | 5% | 10% | 20% | 50% | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G1 | G2 | G1 + G2 | G1 | G2 | G1 + G2 | G1 | G2 | G1 + G2 | G1 | G2 | G1 + G2 | G1 | G2 | G1 + G2 | |
| GLAD4U | 4.2 | 2.7 | 1.9 | 20.3 | 10.3 | 8.1 | 30.6 | 18.6 | 14.4 | 64.5 | 26.9 | 27.4 | 123.6 | 71.0 | 53.0 |
| Disgenet | 0.0 | 0.0 | 0.0 | 2.5 | 1.4 | 0.6 | 5.1 | 2.7 | 1.9 | 6.3 | 5.0 | 3.5 | 12.4 | 7.2 | 5.4 |
| Genie | 11.9 | 6.3 | 4.5 | 27.6 | 8.7 | 10.3 | 50.8 | 51.5 | 36.1 | 273.6 | 146.2 | 107.4 | 389.5 | 247.9 | 174.0 |
| SNP3D | 6.9 | 4.6 | 3.3 | 24.1 | 17.9 | 13.6 | 60.7 | 34.4 | 26.7 | 104.4 | 63.2 | 48.5 | 214.9 | 108.8 | 84.6 |
| Guildify | 97.8 | 39.5 | 31.4 | 97.8 | 120.1 | 78.6 | 424.7 | 226.9 | 169.0 | 1576.3 | 551.4 | 508.5 | 3531.5 | 1863.9 | 1370.9 |
| Cipher | 2.5 | 2.7 | 1.9 | 20.8 | 18.8 | 14.4 | 89.4 | 45.7 | 33.2 | 133.2 | 51.6 | 43.4 | 204.7 | 116.7 | 81.2 |
| Phenolyzer | 95.3 | 45.7 | 36.0 | 355.8 | 191.4 | 147.2 | 441.9 | 323.7 | 221.4 | 461.2 | 399.3 | 264.1 | 532.0 | 444.7 | 298.7 |
| Polysearch | 0.0 | 0.0 | 0.0 | 1.7 | 0.9 | 0.6 | 1.7 | 0.9 | 0.6 | 4.2 | 2.3 | 1.6 | 6.3 | 5.2 | 3.7 |
| Consensus | 91.7 | 66.9 | 46.2 | 372.5 | 271.3 | 189.5 | 510.5 | 400.2 | 277.0 | 989.5 | 430.4 | 356.2 | 1392.2 | 430.4 | 413.5 |