Table 2.

Incidence of thrombosis and bleeding after the index event

	Events, n (%)	Incidence rate % pt-years (95% CI)
After a first thrombosis (N = 1500, total patient-years = 6075)
Thrombotic events	348 (23.2%)	5.7 (5.1–6.4)
Major bleeding	77 (5.1%)	1.3 (1.0–1.6)
After first arterial thrombosis (N = 935, total patient-years = 3907)
Thrombotic events	220 (23.5%)	5.6 (4.9–6.4)
Arterial thrombosis	170 (18.2%)	4.3 (3.7–5.0)
Venous thrombosis	50 (5.3%)	1.3 (0.9–1.7)
Major bleeding	44 (4.7%)	1.1 (0.8–1.5)
After a first venous thrombosis (N = 565, total patient-years = 2168)
Thrombotic events	128 (22.6%)	5.9 (4.9–7.0)
Arterial thrombosis	36 (6.3%)	1.7 (1.2–2.3)
Venous thrombosis	92 (16.3%)	4.2 (3.4–5.2)
Major bleeding	33 (5.8%)	1.5 (1.0–2.1)