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. 2018 Nov 6;9:558. doi: 10.3389/fpsyt.2018.00558

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Copyright © 2018 Wang, Wang, Xu, Qin, Jiang, Khalid, Liu, Pan, Ho and Ho.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effects of minocycline on the MWM test. (A) Average escape latency on the training day, taking into account the times of three sessions (excepted for the session starting in the target quadrant) per day. (B) One of the representative trajectories of the four groups in the water maze on the sixth day within 1 min (origination is opposite to the target quadrant). (C) Number of entries to the target quadrant on the sixth day of testing. (D) Duration of time spent in the target quadrant on the testing day. The results are expressed as the mean ± SEM, n = 10, ^**p < 0.01 vs. control; ^# p < 0.05 vs. PTSD.