Table 2.
HAV-infections: estimated (weighted) prevalence of HAV-specific antibodies due to HAV infection in German children and adolescents (aged 3–17 years) by demographic characteristics and (weighted) results of univariable and multivariable analyses (n = 10,785).
| Characteristic (total no.) | (weighted) prevalence | (weighted) univariable analysis | (weighted) multivariable analysis | ||
|---|---|---|---|---|---|
| % (95% CI) | Odds ratio (95% CI) | p-value | Odds ratio (95% CI) | p-value | |
| Anti-HAV tested and vaccination card available (10,785) | 3.24 (2.87–3.66) | — | — | — | — |
| Age (yearly) | — | 1.08 (1.04–1.11) | <0.001 | 1.07 (1.04–1.11) | <0.001 |
| Sex | |||||
| male (5,552) | 2.91 (2.45–3.46) | ref. | — | — | — |
| female (5,233) | 3.59 (3.06–4.20) | 1.24 (0.99–1.56) | 0.065 | — | — |
| Place of residence | |||||
| North-West (1,423) | 2.42 (1.71–3.42) | ref. | — | ref. | — |
| Central-West (2,676) | 3.63 (3.04–4.32) | 1.51 (1.02–2.26) | 0.042 | 1.31 (0.87–1.97) | 0.193 |
| South-West (3,228) | 3.00 (2.32–3.74) | 1.23 (0.80–1.89) | 0.354 | 1.16 (0.75–1.80) | 0.508 |
| North-East (1,174) | 2.67 (1.86–3.82) | 1.10 (0.66–1.85) | 0.704 | 1.38 (0.80–2.38) | 0.242 |
| Central-East (1,954) | 4.32 (3.09–6.01) | 1.82 (1.11–2.99) | 0.019 | 2.30 (1.37–3.88) | 0.002 |
| Berlin (330) | 5.03 (3.00–8.32) | 2.13 (1.12–4.07) | 0.021 | 1.76 (0.90–3.45) | 0.097 |
| Populationsize of municipality | |||||
| <5,000 (rural area) (2,382) | 3.05 (2.24–4.13) | ref. | — | — | — |
| 5,000–<20,0000 (small town) (2,880) | 2.85 (2.10–3.85) | 0.93 (0.60–1.45) | 0.759 | — | — |
| 20,000–<100,0000 (medium-sized town) (3,147) | 3.13 (2.63–3.73) | 1.03 (0.72–1.48) | 0.873 | — | — |
| >100,000 (large town) (2,376) | 3.95 (3.21–4.85) | 1.31 (0.89–1.92) | 0.165 | — | — |
| Socio-economic status | |||||
| low (2,792) | 4.18 (3.36–5.19) | ref. | — | — | — |
| medium (5,083) | 2.68 (2.20–3.26) | 0.63 (0.47–0.85) | 0.002 | — | — |
| high (2,708) | 2.58 (2.04–3.25) | 0.61 (0.44–0.85) | 0.003 | — | — |
| unknown (202) | — | — | — | — | — |
| Migration status | |||||
| Non-migrant (8,542) | 2.28 (1.94–2.68) | ref. | — | ref. | — |
| One-sided (726) | 2.97 (1.92–4.58) | 1.31 (0.80–2.15) | 0.281 | 1.45 (0.88–2.39) | 0.148 |
| Two-sided (1,479) | 7.76 (6.34–9.48) | 3.60 (2.76–4.70) | <0.001 | 3.84 (2.92–5.04) | <0.001 |
| unknown (38) | — | — | — | — | — |
The results refer to a subsample of study participants with HAV serology but who have not been vaccinated (see Fig. 1).