Table 2.

Biochemical data of all groups.

Groups	db/m	db/db	Metformin (0.196 g/kg)	SWJH (0.978 g/kg)	SWJH (1.957 g/kg)	SWJH (3.914 g/kg)	Berberine (0.157 g/kg)
Body weight (g)	25.2 ± 1.00**	60.7 ± 3.50	58.9 ± 5.70	57.6 ± 2.43	53.3 ± 2.10**	56.0 ± 2.80*	56.5 ± 3.00*
Left kidney weight (g)	0.17 ± 0.01**	0.22 ± 0.01	0.18 ± 0.02**	0.18 ± 0.03*	0.18 ± 0.01**	0.18 ± 0.02**	0.18 ± 0.01**
FBG (mmol/L)	6.0 ± 0.60**	26.5 ± 1.90	17.9 ± 3.10**	23.9 ± 4.00	18.9 ± 5.80*	17.2 ± 7.90*	17 ± 2.10**
BUN (mmol/L)	4.6 ± 0.40**	7.4 ± 1.1	6.1 ± 0.7*	5.1 ± 0.4**	4.6 ± 1.1**	5.0 ± 0.7**	4.7 ± 0.7**
UAE (mg/day)	0.64 ± 0.04**	5.04 ± 1.26	1.40 ± 0.73**	1.69 ± 0.67**	1.14 ± 0.45**	0.78 ± 0.12**	0.60 ± 0.33**
UMAlb (µg/day)	9.5 ± 1.7**	63.6 ± 25.4	28.6 ± 16.7*	20.9 ± 9.3**	33.1 ± 20.4*	18.8 ± 9.8**	16.9 ± 3.8**
Scr (µmol/L)	63.0 ± 5.9**	147.8 ± 14.2	119.1 ± 5.0**	124.4 ± 20.0*	115.2 ± 7.6**	118.9 ± 17.3*	64.3 ± 14.8**
UA(µmol/L)	66.3 ± 13.1**	152.6 ± 41.1	75.9 ± 14.7**	73.7 ± 31.6**	101.2 ± 24.7*	109.3 ± 43.9	96.6 ± 15.7*
TGF-β1 (×1000 pg/ml)	6.2 ± 3.0**	16.6 ± 5.8	6.5 ± 3.0**	4.7 ± 0.9**	5.4 ± 0.8**	7.8 ± 3.0*	5.3 ± 1.1**
VEGF (pg/ml)	184.5 ± 17.2*	205.7 ± 5.9	212.0 ± 22.8	179.2 ± 28.8	224.7 ± 25.7	197.1 ± 34.1	188.1 ± 17.3*

Data expressed as mean ± SD, *P < 0.05, **P < 0.01 compared with db/db group (n = 6).