Fig. 3.

a Prominent ectatic vessels can be mistaken for reactive lesion or benign hemangioma if KS is not considered. b Florid granulation tissue on top of the mucosal lesions is a frequent feature, which may obscure the underlying tumor (the few scattered tumor cells are highlighted by HHV8 immunostain in the inset). c This HIV-unrelated lesion from the ear showed prominent inflammatory reaction adjacent to and within the lesion. d Fibrosarcoma-like histology from same tumor (note absence of kaposiform features). e Uniform strong nuclear reactivity for ERG. f HHV8 was expressed in all cases