Table 3.

HER-2 results by immunohistochemistry

Result	Criteria
Negative (0)	No staining or incomplete, faint membrane staining in ≤ 10% of invasive tumor cells
Negative (1+)	Incomplete, faint membrane staining in > 10% of invasive tumor cells
Equivocal (2+)	Incomplete and/or weak to moderate circumferential membrane staining in > 10% of invasive tumor cells or complete, intense, circumferential membrane staining in ≤ 10% of invasive tumor cells
Positive (3+)	Complete, intense, circumferential membrane staining in > 10% of invasive tumor cells