Table 3.
The Milan System for reporting salivary gland cytopathology for cystic lesions
Diagnostic category | Example of cystic salivary gland lesion |
---|---|
Non-diagnostic | Cystic non-mucinous fluid only |
Non-neoplastic | Inflammatory cyst with amylase crystalloids |
Atypia of undetermined significance | Histiocytes ± scant epithelial cells in a background of abundant mucin (cannot exclude low-grade mucoepidermoid carcinoma) |
Benign neoplasm | Warthin tumor, or cystic pleomorphic adenoma |
Salivary gland neoplasm of uncertain malignant potential (SUMP) | Cellular oncocytic/oncocytoid neoplasm with cystic background (differential includes Warthin tumor or oncocytic cystadenoma) |
Suspicious for malignancy | Atypical cells in a mucinous background, suspicious for low-grade mucoepidermoid carcinoma |
Malignant | Keratinizing squamous cell carcinoma |