Skip to main content
. 2018 Mar 9;12(4):548–561. doi: 10.1007/s12105-018-0904-8

Table 3.

The Milan System for reporting salivary gland cytopathology for cystic lesions

Diagnostic category Example of cystic salivary gland lesion
Non-diagnostic Cystic non-mucinous fluid only
Non-neoplastic Inflammatory cyst with amylase crystalloids
Atypia of undetermined significance Histiocytes ± scant epithelial cells in a background of abundant mucin (cannot exclude low-grade mucoepidermoid carcinoma)
Benign neoplasm Warthin tumor, or cystic pleomorphic adenoma
Salivary gland neoplasm of uncertain malignant potential (SUMP) Cellular oncocytic/oncocytoid neoplasm with cystic background (differential includes Warthin tumor or oncocytic cystadenoma)
Suspicious for malignancy Atypical cells in a mucinous background, suspicious for low-grade mucoepidermoid carcinoma
Malignant Keratinizing squamous cell carcinoma