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. 2018 Nov 6;9:1175. doi: 10.3389/fphar.2018.01175

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Copyright © 2018 Kim, Lee, Kim, Kwon, Park, Lee, Jung and Jeoung.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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SOCS1 regulates the expression of miR-122a-5p and MIP-2. (A) Immunohistochemical staining by employing the indicated antibody was performed. Scale bar represents 10 μm. Skin tissues of BALB/c mice of each experimental group were isolated at the time of sacrifice and were also subjected to H&E staining. Toluidine blue staining was performed to determine the number of degranulated mast cells. Closed triangle represents degranulated mast cells. (B) Tissue lysates from mouse of each experimental group were subjected to qRT-PCR analysis. ^∗p < 0.05; ^∗∗∗p < 0.0005. The number of degranulated mast cells was also determined. Closed triangle represents degranulated mast cells. Scale bars represent 100 μm.