2.
Relationship between clinicopathological characteristics and ELN count of GC patients (N=7,620)
| Characteristics | Cases for ELN count [n (%)] | χ2 | P | Likelihood ratio
test P value |
BIC value | ||
| <16 | 16−30 | >30 | |||||
| ELN, examined lymph node; GC, gastric cancer; TG, total gastrectomy; DG, distal gastrectomy; PG, proximal gastrectomy; BIC, Bayesian information criterion. The eighth edition of TNM classification for GC was adopted for postoperatively pathological stages of all included patients. | |||||||
| Gender | 22.949 | <0.001 | 0.041 | 6,180 | |||
| Male | 1,699 (22.3) | 2,432 (31.9) | 1,247 (16.4) | ||||
| Female | 593 (7.8) | 1,050 (13.8) | 599 (7.9) | ||||
| Age at surgery (year) | 90.274 | <0.001 | <0.001 | 6,223 | |||
| <60 | 1,020 (13.4) | 1,883 (24.7) | 1,083 (14.2) | ||||
| ≥60 | 1,272 (16.7) | 1,599 (21.0) | 763 (10.0) | ||||
| Tumor location | 398.163 | <0.001 | <0.001 | 6,223 | |||
| Upper third | 899 (11.8) | 857 (11.2) | 267 (3.5) | ||||
| Middle third | 283 (3.7) | 688 (9.0) | 503 (6.6) | ||||
| Lower third | 900 (11.8) | 1,656 (21.7) | 931 (12.2) | ||||
| >2/3 stomach | 210 (2.8) | 281 (3.7) | 145 (1.9) | ||||
| Tumor size (cm) | 19.963 | <0.001 | 0.029 | 6,181 | |||
| ≤4.0 | 1,126 (14.8) | 1,705 (22.4) | 795 (10.4) | ||||
| >4.0 | 1,166 (15.3) | 1,777 (23.3) | 1,051 (13.8) | ||||
| Lauren classification | 16.818 | <0.001 | 0.392 | ||||
| Intestinal | 1,034 (13.6) | 1,465 (19.2) | 716 (9.4) | ||||
| Diffuse | 1,258 (16.5) | 2,017 (26.5) | 1,130 (14.8) | ||||
| Type of gastrectomy | 500.060 | <0.001 | <0.001 | 6,291 | |||
| TG | 360 (4.7) | 774 (10.2) | 607 (8.0) | ||||
| DG | 1,129 (14.8) | 2,018 (26.5) | 1,083 (14.2) | ||||
| PG | 803 (10.5) | 690 (9.1) | 156 (2.0) | ||||
| pT stage | 66.037 | <0.001 | <0.001 | 6,195 | |||
| T1 | 276 (3.6) | 455 (6.0) | 214 (2.8) | ||||
| T2 | 383 (5.0) | 654 (8.6) | 372 (4.9) | ||||
| T3 | 313 (4.1) | 560 (7.3) | 375 (4.9) | ||||
| T4a | 1,189 (15.6) | 1,576 (20.7) | 763 (10.0) | ||||
| T4b | 131 (1.7) | 237 (3.1) | 122 (1.6) | ||||
| pN stage | 745.581 | <0.001 | <0.001 | 6,902 | |||
| N0 | 1,031 (13.5) | 1,203 (15.8) | 559 (7.3) | ||||
| N1 | 495 (6.5) | 613 (8.0) | 256 (3.4) | ||||
| N2 | 522 (6.9) | 646 (8.5) | 319 (4.2) | ||||
| N3a | 244 (3.2) | 762 (10.0) | 332 (4.4) | ||||
| N3b | 0 (0) | 258 (3.4) | 380 (5.0) | ||||