2.

Surgical and pathological characteristics (N=100)

Variable	Neoadjuvant group [n (%)]			Adjuvant group [n (%)]
	SOX (N=25)	CapeOX (N=25)		SOX (N=25)	CapeOX (N=25)
SOX, oxaliplatin plus S-1; CapeOX, oxaliplatin plus capecitabine.
Gastrectomy
Total	13 (52)	12 (48)		11 (44)	15 (60)
Distal	11 (44)	13 (52)		14 (56)	10 (40)
Proximal	1 (4)	0 (0)		0 (0)	0 (0)
Site of tumor
Upper 1/3	7 (28)	6 (24)		5 (20)	9 (36)
Middle 1/3	8 (32)	9 (36)		8 (32)	8 (32)
Proximal 1/3	10 (40)	10 (40)		12 (48)	8 (32)
Combined resection (yes)	1 (4)	1 (4)		0 (0)	5 (20)
Bleeding (mL) [median (range)]	100 (50−300)	100 (50−250)		100 (50−300)	100 (50−400)
Duration (min) [median (range)]	200 (145−350)	205 (130−490)		200 (140−460)	230 (150−480)
Hospital stay (day) [median (range)]	11 (9−57)	12 (8−34)		13 (9−52)	13 (8−64)
Postoperative complications
Bleeding	1 (4)	2 (8)		0 (0)	1 (4)
Anastomotic leakage	2 (8)	1 (4)		2 (8)	3 (12)
Abdominal abscess	1 (4)	1 (4)		4 (16)	2 (8)
Pancreas fistula	0 (0)	0 (0)		0 (0)	1 (4)
Pneumonia	3 (12)	0 (0)		1 (4)	2 (8)
Emptying disorder	2 (8)	0 (0)		0 (0)	0 (0)
Ileus	0 (0)	0 (0)		0 (0)	1 (4)
Pleural effusion	2 (8)	3 (12)		1 (4)	4 (16)
Reoperation	2 (8)	2 (8)		0 (0)	1 (4)
Mortality	1 (4)	0 (0)		0 (0)	1 (4)
R0 margin (yes)	25 (100)	25 (100)		24 (96)	25 (100)
LN dissection ( )
No. dissected	34.6±16.1	30.1±11.7		36.2±11.5	35.3±13.2
No. positive	2.6±5.2	3.4±5.2		6.2±8.9	4.4±5.4
Pathological T
T0	3 (12)	1 (4)		0 (0)	0 (0)
T1	2 (8)	2 (8)		2 (8)	3 (12)
T2	9 (36)	8 (32)		5 (20)	6 (24)
T3	2 (8)	5 (20)		2 (8)	4 (16)
T4	9 (36)	9 (36)		16 (64)	12 (48)
Pathological N
N0	15 (60)	11 (44)		6 (24)	7 (28)
N1	4 (16)	5 (20)		5 (20)	7 (28)
N2	2 (8)	4 (16)		7 (28)	6 (24)
N3	4 (16)	5 (20)		7 (28)	5 (20)
Vascular emboli (yes)	1 (4)	4 (16)		10 (40)	8 (32)