Figure 2.

T cell-specific BACH2 does not influence disease outcome in P. chabaudi infection. (A) Blood parasitemia was measured on days 1–8 p.i. (n = 12 mice per group), and days 9–14 p.i. (n = 6 mice per group). Whole body weights (B), spleen weights (C), and numbers of splenic leukocytes (D) were measured in B6.Bach2^ΔT (open triangles) and B6.Bach2^fl/fl (closed circles) mice infected with P. chabaudi at days 0, 7, and 14 p.i., n = 5–7 B6.Bach2^ΔT and n = 5 B6.Bach2^fl/fl mice at each time point, mean ± SEM, significance assessed by Mann-Whitney U-test.