Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Nov 6;11:399. doi: 10.3389/fnmol.2018.00399

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Gouveia Roque and Holt.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Retinal ganglion cell (RGC) origin dictates distinct growth cone mTOR activation profiles in response to Ephrin-A1. (A–C) Nasal and temporal stage 32 retinal explants grown in vitro for 24 h were stimulated with Ephrin-A1-Fc at a concentration of 5 μg/mL, and stained with an antibody that specifically recognizes ribosomal protein S6 (rpS6) when phosphorylated at Ser-235/236. Representative micrographs of control (clustered Fc)- and Ephrin-A1-treated RGC growth cones are shown (mean ± SEM; n = no. of growth cones analyzed; ***P < 0.0001, one-way ANOVA). Scale bar: 5 μm.