Table 2.

Brain responses [2b-0b across all conditions].

Regions	X, Y, Z	T	P-value
One-way Anova – brain activations for all subjects
Thalamus dorsal [a]	12 –6 10	11.31	<0.001
	–10 –6 10	9.87	<0.001
Thalamus [b]	14 –6 10	11.57	<0.001
	–12 –12 6	12.36	<0.001
Occipital (Ccalcarine) [c]	–8 –78 10	7.19	<0.001
	12 –70 14	6.81	<0.001
	4 –72 12	6.35	0.005
Intraparietal sulcus (IPS) [d]	–32 –43 51	6.33	<0.001
	32 –44 50	5.93	<0.001
	34 –48 48	10.10	<0.001
Fusiform [e]	–44 –60 –14	5.86	<0.001
Dorsolateral prefrontal cortex (DLPFC) [f]	44 36 32	9.07	<0.001
	–46 32 36	9.67	<0.001
Supplemental motor area (SMA) [g]	6 12 52	10.94	<0.001
	–4 14 50	13.89	<0.001
Insula/fronto-insular [h]	32 24 –2	17.45	<0.001
	–32 22 0	15.26	<0.001
	32 26 2	15.45	<0.001
	–28 28 2	11.52	<0.001
Motor/Ppremotor [i]	–44 6 34	15.31	<0.001
Superior parietal gyrus (SPG) [j]	–26 –58 –62	6.34	<0.001
	28 58 60	8.71	<0.001
Cerebellum [k]	28 –60 –30	14.99	<0.001
	30 –66 –48	13.52	<0.001
	–32 –54 –30	13.15	<0.001
Orbiofrontal Ccortex (OFC) [l]	24 44 –14	9.08	<0.001
Cingular [m]	4 8 28	8.11	<0.001
Temporal Iinferior [n]	–52 –60 –10	9.08	<0.001
	56 –46 –10	8.63	<0.001
Temporal Ssuperior	–58 –24 2	6.03	0.01
Caudate [o]	16 0 10	12.16	<0.001
	–12 2 6	11.13	<0.001
Putamen [p]	28 20 2	14.68	<0.001
	–26 14 4	10.43	<0.001
Young > Older-NL and Older-IOL
IntraPparietal Ssulcus (IPS) [q]	30 –40 36	8.19	<0.001
	–28 –40 36	6.20	<0.004
Older-NL and Older-IOL > Young
ACC/MPFC [r]	0 48 2	6.53	<0.004
	–10 46 0	6.34	<0.008
Mid-cingular [s]	–2 –14 36	6.81	<0.002
Precuneus (PCC) [t]	–2 –44 32	7.32	<0.001
	–6 –36 38	6.28	<0.002
Parietal superior and posterior [u]	–50 –56 48	6.19	<0.009
	–38 –68 40	6.14	<0.02
Frontal superior [v]	–12 44 48	6.27	<0.008
Frontal inferior [x]	–20 54 –2	7.05	<0.001
Angular gyrus	–46 –54 32	6.88	<0.002

Brain responses to the n-back task [2b-0b] irrespective of light condition. Letters between [ ] correspond to letters of Figure 3. P < 0.05 values corrected for multiple comparisons over the entire brain volume (family wise error approach).