FIG 1.

Time course of HCV infection of Huh7.5 cells and pDC coculture. (a) Kinetics of infectious HCV progeny production by the indicated viruses at an MOI of 0.1 TCID₅₀/cell. (b) Infectious HCV progeny production (virus indicated in abscissa) following Huh7.5 infection and stimulated or unstimulated pDCs (left) and percentage of TCID₅₀/ml inhibition relative to the yield of the infection without pDC coculture (“control” [right]). The experiments were performed with Jc1 virus, the HCV wild-type virus, with IR, the IFN-α-resistant virus, and with P100, the high-replication virus, as described in Materials and Methods. Results represent one of two independent experiments.