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. 2018 Nov 6;12:398. doi: 10.3389/fncel.2018.00398

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Copyright © 2018 García-Domínguez, Veselá, García-Revilla, Carrillo-Jiménez, Roca-Ceballos, Santiago, de Pablos and Venero.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of LPS and MPTP on the expression of TNF-α, IFN-β, IL-1β, and IL-6 mRNAs in the striatum and SN. Quantification of mRNAs expression was made by real-time RT-PCR. Results are mean ± SD of at least three independent experiments, and are expressed as percentage of controls. Statistical signification: One-way ANOVA followed by the LSD post hoc test for multiple range comparisons; a, compared with control; b, compared LPS; c, compared with MPTP. (A) TNF-α mRNA in striatum, p < 0.001; (B) INF-β mRNA in striatum, p < 0.001; (C) IL-6 mRNA in striatum, p < 0.01; (D) IL-1β mRNA in striatum; (E) TNF-α mRNA in SN, p < 0.001; (F) INF-β mRNA in SN, p < 0.001; (G) IL-6 mRNA in SN, p < 0.001; (H) IL-1β mRNA in SN.