Table 4.
Eosinophil, neutrophil sputum percentage, total IgE serum concentration, IL-25 mRNA expression and protein concentration in induced sputum from asthma patients with and without atopy
| Parameter | Non-atopic patients (n = 18) | Atopic patients (n = 20) | P-value |
|---|---|---|---|
| Eosinophils (%) | 2 (0–5) | 5 (2–23) | 0.043 |
| Neutrophils (%) | 47 (42–57) | 52 (31–68) | 0.864 |
| IgE [IU/ml] | 33.5 (11.7–56.5) | 152 (58–341) | 0.006 |
| IL-25 mRNA (fold change) | 0.6 (0.1–11.3) | 0.25 (0.1–0.7) | 0.316 |
| IL-25 [pg/ml] | 331.5 (261.5–435) | 448.8 (361.6–605.2) | 0.030 |
Values expressed as median and IQR, p-value obtained in Mann-Whitney U test.