Table 2.
Factors associated with serum hepcidin concentration in multiple linear regression models
|
Correlation analysis |
Linear regression analysis |
|||
| Characteristic | rho | P-value | Effect size | P -value |
| Age (yr) | 0.3 | < 0.01 | 0.213 | 0.001 |
| Gender | 0.01 | 0.986 | - | - |
| ALT (U/L) | -0.095 | 0.141 | - | - |
| AST (U/L) | -0.013 | 0.842 | - | - |
| GGT (U/L) | 0.011 | 0.871 | - | - |
| AKP (U/L) | 0.123 | 0.058 | - | - |
| ALB (g/L) | -0.055 | 0.394 | - | - |
| TBIL (μmol/L) | 0.108 | 0.096 | - | - |
| TBA (μmol/L) | 0.196 | 0.002 | ||
| HBV-DNA (Log10) | -0.374 | < 0.01 | -0.282 | < 0.001 |
| APRI | 0.114 | 0.077 | - | - |
| RBC (× 1012/L) | -0.153 | 0.018 | ||
| WBC (× 109/L) | -0.119 | 0.065 | - | - |
| PLT (× 109/L) | -0.195 | 0.002 | ||
| HGB (g/L) | -0.158 | 0.014 | ||
| MCV (fL) | 0.01 | 0.879 | - | - |
| HCT (L/L) | -0.162 | 0.012 | ||
| INR | 0.188 | 0.003 | 0.198 | < 0.001 |
| Serum iron (μmol/L) | 0.027 | 0.672 | - | - |
| Total iron binding capacity (μmol/L) | -0.073 | 0.261 | - | - |
| Serum ferritin (μg/L) | -0.13 | 0.836 | - | - |
| Transferrin saturation (%) | 0.056 | 0.387 | - | - |
| transferrin (g/L) | 0.002 | 0.98 | - | - |
ALT: Alanine aminotransferase; AST: Aspartate transaminase; AKP: Alkaline phosphatase; ALB: Albumin; APRI: AST to platelet ratio index; HBV: Hepatitis B virus; TBIL: Total bilirubin; RBC: Red blood cell count; WBC: White blood cell count; TBIL: Total bilirubin; TBA: Total bile acid; HGB: Hemoglobin; HCT: Hematocrit; PLT: Platelets; MCV: Mean corpuscular volume; INR: International normalized ratio.