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Histological findings. A and B: Lymph node biopsy showing diffuse infiltration of malignant lymphoid cells (A: HE, ×100, B: ×400). Immunohistochemical staining for (C) CD20(+), (D) CD3(+), and (E) CD56(+) (× 400). F: In situ hybridization showing EBV-encoded small RNA positivity, with most cells showing strongly positive staining (×400). HE: Hematoxylin and eosin; EBV: Epstein-Barr virus.
