Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
High throughput alkaline COMET assay shows increased DNA damage in F10 and Chk1i (PF-477736) combination.
(A) HCT-116 cells were treated with F10 (250 nM) and/or PF-477736 (1.65 μM) for 24 or 48 hours and analyzed for DNA damage by COMET assay. (B) Combination of F10 and PF-477736 shows increased % tail DNA (DNA damage) compared to the individual treatments.
