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. Author manuscript; available in PMC: 2019 Oct 18.
Published in final edited form as: Cell. 2018 Oct 18;175(3):679–694.e22. doi: 10.1016/j.cell.2018.09.004

Figure 7. Short-Term ICD Feeding Induces Hyperbilirubinemia, Apoptosis, and Neutrophil Infiltration in the Liver of T5KO Mice.

Figure 7.

(A–D) One-month ICD fed group: (A) serum appearance, (B) total bilirubin, (C) ALT, and (D) gross liver.

(E–G) TUNEL-stained liver sections: (E) WT, (F) T5KO-NB, and (G) T5KO-HB. Positive cells in green, DAPI in blue. Scale bars, 50 μm (E and F); 100 μm (G).

(H) Liver KC.

(I) Serum sICAM-1.

(J-O) Hepatic (J) neutrophils (K) MPO (L) NE (M) ROS (N) MDA (O) 8-hydroxy-2’-guanosine (8-OH-dG) in serum and urine.

See also Figures S5 and S7