FIGURE 7:

Disorganization of sarcomeres in loss-of-function mutants for PP2A B (SUR-6), B” (RSA-1), and B”’(CASH-1) subunits. Immunofluorescence images of portions of several body-wall muscle cells reacted with antibodies to MHC A from wild type, the temperature-sensitive mutant sur-6(or550), the maternal-effect lethal mutants rsa-1(dd10) and rsa-1(dd13), and cash-1(RNAi). There is clear disorganization of A-bands in sur-6(or550) and cash-1(RNAi). In the case of the rsa-1 mutants, although there are normal straight parallel A-bands, these A-bands appear as doublets, seen at higher resolution in Figures 9 and 10. Scale bar, 20 μm.