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. 2018 Aug 15;29(17):2084–2097. doi: 10.1091/mbc.E18-03-0192

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© 2018 Qadota et al. “ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society for Cell Biology.

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FIGURE 8: — Split or doublet MHC A localization is also found in MHC B myosin head mutants. Immunolocalization of UNC-95 (marker for M-lines and dense bodies) and MHC A in muscle of wild type, rsa-1, and special unc-54 mutants. Insets show higher-magnification views. Whereas wild type shows single tight MHC A localization, both rsa-1 mutants and unc-54 mutants show closely spaced doublet MHC A localization. unc-54(s74), unc-54(s95), and unc-54(st134) are rare missense mutations in the head domain of MHC B. Scale bar, 10 μm.