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. 2018 Aug 15;29(17):2084–2097. doi: 10.1091/mbc.E18-03-0192

TABLE 1:

PP2A components in muscle

Muscle expression
Gene Encoding Promoter SAGE Muscle localization Muscle phenotype
let-92 Catalytic subunit (C) Yes Yes ND Detach muscle, jack-knife (L1 feeding RNAi)
paa-1 Scaffolding subunit (A) Yes Yes I-band Detach muscle, jack-knife (L1 feeding RNAi)
sur-6 Regulatory subunit (B) No Yes I-band Disorganized myofilaments (ts mutant)
pptr-1 Regulatory subunit (B’)/B56 Yes No I-band Disorganized myofilaments (deletion mutant)
pptr-2 Regulatory subunit (B’)/B56 Yes Yes M-lines and dense bodies Normal muscle (deletion mutant)
rsa-1 Regulatory subunit (B’’) ND Yes M-lines and I-bands Split MHCA (maternal effect lethal mutants)
cash-1 Regulatory subunit (B’’’)/striatin No Yes ND Disorganized myofilaments (RNAi)