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. 2018 Sep;56(3):312–328. doi: 10.17113/ftb.56.03.18.5658

Table 2. Commercially available keratinase products.

Application Description of the product Commercial product Reference
Earwax removal Successful, safe and effective removal of earwax from the external ear canal Zymox (72)
Corn and callus removal Keratinases present natural alternative to the use of acids for corn and callus removal Keratoclean® Hydra PB, PURE 100 Keratinase (72)
Acne treatment Acne is caused by blockage of sebaceous glands in the presence of large quantities of keratin, therefore keratinases can be used for successful treatment Keratoclean® Sensitive PB, Keratopeel® PB (72, 119)
Commercial use (poultry feed) Keratinase product improves the feed ratio and has a positive effect on chicken body mass Versazyme® (72)
Commercial use (poultry feed) Enzyme product reduces cost of cooking and temperature processing of feather, therefore increasing the digestibility and nutritional value of feed Valkerase® (72)
Prion decontamination Effective decontamination of medical instruments from prions. It contains engineered protease with increased activity, broader specificity and thermostability PrionzymeTM (72)
Biomedical, pharmaceutical and cosmetics Keratinase product is supposed to regulate the concentration of keratin in pores, therefore helping to eliminate blisters, keratinized skin, it can be used for treatment of dermatophytic and nail diseases, scars and epithelial regeneration PURE100 Keratinase (72)
Cleaning agents Cleaning pipes and tanks with different enzymes, including keratinases Bioguard Plus (72)