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. 2018 Nov 6;9:1239. doi: 10.3389/fphar.2018.01239

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Copyright © 2018 Liu, Zhu, Liu, Li, Chen, Jia, Wang, Ma, Tian, Wang, Fu, Niu, Orekhov, Gao, Zhang and Zhao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MF preserved bone strength, biomechanical, and material properties in the femurs of diabetic rats. (A–C) Show cortical area ratio, cortical thickness, and trabecular area ratio in different groups of rats determined by μCT Scanning. (D–F) Show the results of three-point bending examination of ultimate load, elastic modulus, and bending strength in different groups of rats. (G–I) Show the results of fatty acid/collagen, collagen maturity, and mineral/matrix detected by FTIR spectrum. Data are presented as mean ± SD. n = 9. ^#p < 0.05 or ^##p < 0.01 compared with NC group, *p < 0.05 or **p < 0.01 compared with DM group.