Table 3.

Branch-associated PSGs related to adaptations to hypoxia (Fig. 2) in high-elevation frogs and lizards

Branch	Elevational shift	Frog PSGs	Lizard PSGs
1	∼3,500 to ∼4,500 m	FMN2, KIAA0196, BMPR2, TYW5, B4GALT7, B3GAT2, IMPDH1, ADCY4, RRM2B, GMDS, GPAA1, ENSACAG00000002886, AP2A1, PPP4R3A, ADIPOR1, GPER1, PLCD1, SCARB1, ALDOA, HIPK2, F7, POSTN, ADAM17, FN1, ITIH4, FLNA	BAG3, RAC1, ENSACAG00000008899, ZRANB3, DSCC1, NBN, GTSE1
2 and 6	∼2,000 to ∼3,500 m	EPHA2, PTK7, BMP4, RXRA, PBX1, COL3A1, STARD13, EZR, SLC26A4, CA12, SPHK1, PTGFR, PPP3CB, SLC37A3, SLC37A2, SLC35F6, UBE4B, IPO9, FLOT2, CRTAP, CEP83, NLRX1, ENSACAG00000025660	ADK, PPP1R1A, PPP1R3B, JAK2, FYN, CDKL5, AARS, ATF6, RAC1
3 and 7	Lowlands to ∼2,000 m	XRCC6, FBXL3, PRKAA1, CLK2, ENSACAG00000013018, COL3A1, MAPK8, MEN1, CCKAR, FGG, TNFAIP3, STX4, SCARB1, ENSACAG00000002091, ENSACAG00000022125, ENSACAG00000009367, SERPINC1, F5, MBD1, ENSACAG00000015535, ENSACAG00000015364, FKBP4, HSPH1, ENSACAG00000017064, HSPG2, COASY, CANT1, MAT2B, TYW5, ALG3, UPP2, FGFR1, EZR, CEP120, PPIL2, PDIA4, PRDX4, CCT4, TBCE, PDIA3, PPP1R15B, PLA2G6, FLOT1, GATA1, THY1, GAS6, KEAP1, TPR, SEMA4D, CTNND1, VEGFA, NOC2L, PLS1	APOA1BP, PGM2, IMPA1, PPP1R2, PAFAH1B1, NPHS2, MYL6, FRMD1