Fig. 4.

Hydrodynamic radii of WT and mutant DENV2 RNAs. (A) Dynamic light scattering curves from individual experiments, representative of multiple replicate experiments. The mean radius values for WT, Env^mut, and NS2A^mut are 54, 81, and 75 nm, respectively. (B) RNA radii of WT and mutant RNAs. Values are mean and SD calculated from four experiments. Control NS5^mut is denoted by an open symbol.