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. 2018 Nov 13;8:16743. doi: 10.1038/s41598-018-35106-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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ME1 expression is upregulated in BLBC. (a–e) ME1 expression was obtained from five publicly available gene expression datasets, including GSE25066 (a), NKI295 (b), TCGA (c), GSE7390 (d) and GSE1456 (e). Scatter dot-plots indicated ME1 expression in basal-like and other subtype of breast cancer from these datasets. (f) Expression of ME1 was examined by western blotting in tumor samples from five cases of luminal and five cases of triple-negative breast cancer. (g) Expression of ME1 in two luminal and five BLBC cell lines was analyzed by western blotting.