Table 1.
Results of GO enrichment analysis
| Cell type | Experiments | GO ID | Name | p-Value |
|---|---|---|---|---|
| Retina | 2 | GO:0050877 | Nervous system process | 7.63e−09 |
| GO:0050953 | Sensory perception of light stimulus | 7.63e−09 | ||
| GO:0007601 | Visual perception | 7.63e−09 | ||
| GO:0007423 | Sensory organ development | 8.69e−09 | ||
| GO:0060041 | Retina development in camera-type eye | 8.69e−09 | ||
| GO:0007600 | Sensory perception | 4.09e−08 | ||
| GO:0001654 | Eye development | 3.96e−07 | ||
| GO:0003008 | System process | 6.67e−07 | ||
| GO:0009584 | Detection of visible light | 6.86e−07 | ||
| GO:0043010 | Camera-type eye development | 1.23e−06 | ||
| Dorsal root ganglion | 3 | GO:0019233 | Sensory perception of pain | 3.54e−06 |
| GO:0016048 | Detection of temperature stimulus | 9.86e−06 | ||
| GO:0031175 | Neuron projection development | 2.41e−04 | ||
| GO:0050965 | Detection of temperature stimulus involved in… | 2.51e−04 | ||
| GO:0050877 | Nervous system process | 2.51e−04 | ||
| GO:0050961 | Detection of temperature stimulus involved in… | 2.51e−04 | ||
| GO:0048666 | Neuron development | 3.49e−04 | ||
| GO:0009581 | Detection of external stimulus | 3.79e−04 | ||
| GO:0009582 | Detection of abiotic stimulus | 3.79e−04 | ||
| GO:0007600 | Sensory perception | 4.31e−04 | ||
| Skin epidermis | 2 | GO:0009888 | Tissue development | 2.99e−06 |
| GO:0043588 | Skin development | 2.99e−06 | ||
| GO:0042303 | Molting cycle | 9.57e−05 | ||
| GO:0042633 | Hair cycle | 9.57e−05 | ||
| GO:0030177 | Positive regulation of Wnt signaling pathway | 1.16e−04 | ||
| GO:0042476 | Odontogenesis | 1.16e−04 | ||
| GO:0009653 | Anatomical structure morphogenesis | 1.87e−04 | ||
| GO:0022404 | Molting cycle process | 2.37e−04 | ||
| GO:0030111 | Regulation of Wnt signaling pathway | 2.37e−04 | ||
| GO:0022405 | Hair cycle process | 2.37e−04 | ||
| T cell | 4 | GO:0002376 | Immune system process | 4.68e−10 |
| GO:0006955 | Immune response | 3.86e−08 | ||
| GO:0046649 | Lymphocyte activation | 1.25e−07 | ||
| GO:0045321 | Leukocyte activation | 1.25e−07 | ||
| GO:0002682 | Regulation of immune system process | 1.25e−07 | ||
| GO:0042110 | T cell activation | 2.75e−07 | ||
| GO:0050776 | Regulation of immune response | 2.84e−07 | ||
| GO:0002684 | Positive regulation of immune system process | 3.82e−07 | ||
| GO:0001775 | Cell activation | 4.54e−07 | ||
| GO:0002252 | Immune effector process | 6.38e−07 |
Top 10 enriched “GO: Biological Process” terms using top 50 upregulated DE genes for each cell type (FDR adjusted p-values). “Experiments” refers to the number of studies used to compute differentially expressed genes (Methods)