Fig. 4.

Purification of USP14 interacting proteins and identification of potential USP14 substrates. a The immunoprecipitation of Flag-USP14 interacting protein was visualized by Coomassie blue staining. b Venn diagram showing the number of downregulated proteins identified in response to USP14 KD (green), USP14 interaction candidates identified in Co-IP process (blue), upregulated ubiquitin sites identified in response to USP14 KD (red) and overlapping proteins in the datasets. The chart below shows potential substrates of the overlapped proteins