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. 2018 Nov 13;8:16767. doi: 10.1038/s41598-018-35175-z

Table 1.

Characteristics of study participants by treatment groups.

Total Allopurinol or febuxostat Allopurinol plus fenofibrate or febuxostat plus fenofibrate P-value
N % n % n %
Total 863 793 70
Sex 0.026
   Male 789 91.4 720 90.8 69 98.6
   Female 74 8.6 73 9.2 1 1.4
Age, years 0.014
   –29 53 6.1 51 6.4 2 2.9
   30–39 171 19.8 148 18.7 23 32.9
   40–49 208 24.1 190 24.0 18 25.7
   50–59 194 22.5 180 22.7 14 20.0
   60–69 124 14.4 113 14.2 11 15.7
   70– 113 13.1 111 14.0 2 2.9
Age (mean/SD) 50.6 14.9 50.9 15.1 46.9 12.0 0.012
Hypertension 0.013
   No 469 54.3 421 53.1 48 68.6
   Yes 394 45.7 372 46.9 22 31.4
Hyperlipidemia <0.0001
   No 563 65.2 554 69.9 9 12.9
   Yes 300 34.8 239 30.1 61 87.1
Diabetes mellitus 0.806
   No 736 85.3 677 85.4 59 84.3
   Yes 127 14.7 116 14.6 11 15.7
Colchicine 0.683
   No 661 76.6 606 76.4 55 78.6
   Yes 202 23.4 187 23.6 15 21.4
Glucocorticoids 0.247
   No 627 72.7 572 72.1 55 78.6
   Yes 236 27.3 221 27.9 15 21.4
NSAIDs 0.156
   No 628 72.8 572 72.1 56 80.0
   Yes 235 27.2 221 27.9 14 20.0
HMG-CoA reductase inhibitor 0.780
   No 820 95.0 753 95.0 67 95.7
   Yes 43 5.0 40 5.0 3 4.3
Angiotensin receptor 0.424
   No 812 94.1 744 93.8 68 97.1
   Yes 51 5.9 49 6.2 2 2.9
Year of diagnosis 0.904
   1995–2000 11 1.3 10 1.3 1 1.4
   2001–2005 124 14.4 114 14.4 10 14.3
   2006–2010 215 24.9 195 24.6 20 28.6
   2011–2015 343 39.7 315 39.7 28 40.0
   2016–2018 170 19.7 159 20.1 11 15.7

SD: standard deviation; NSAIDs: nonsteroidal anti-inflammatory drugs; HMG-CoA: 3-hydroxy-3-methylglutaryl-CoA.