Table 1.
Total | Allopurinol or febuxostat | Allopurinol plus fenofibrate or febuxostat plus fenofibrate | P-value | ||||
---|---|---|---|---|---|---|---|
N | % | n | % | n | % | ||
Total | 863 | 793 | 70 | ||||
Sex | 0.026 | ||||||
Male | 789 | 91.4 | 720 | 90.8 | 69 | 98.6 | |
Female | 74 | 8.6 | 73 | 9.2 | 1 | 1.4 | |
Age, years | 0.014 | ||||||
–29 | 53 | 6.1 | 51 | 6.4 | 2 | 2.9 | |
30–39 | 171 | 19.8 | 148 | 18.7 | 23 | 32.9 | |
40–49 | 208 | 24.1 | 190 | 24.0 | 18 | 25.7 | |
50–59 | 194 | 22.5 | 180 | 22.7 | 14 | 20.0 | |
60–69 | 124 | 14.4 | 113 | 14.2 | 11 | 15.7 | |
70– | 113 | 13.1 | 111 | 14.0 | 2 | 2.9 | |
Age (mean/SD) | 50.6 | 14.9 | 50.9 | 15.1 | 46.9 | 12.0 | 0.012 |
Hypertension | 0.013 | ||||||
No | 469 | 54.3 | 421 | 53.1 | 48 | 68.6 | |
Yes | 394 | 45.7 | 372 | 46.9 | 22 | 31.4 | |
Hyperlipidemia | <0.0001 | ||||||
No | 563 | 65.2 | 554 | 69.9 | 9 | 12.9 | |
Yes | 300 | 34.8 | 239 | 30.1 | 61 | 87.1 | |
Diabetes mellitus | 0.806 | ||||||
No | 736 | 85.3 | 677 | 85.4 | 59 | 84.3 | |
Yes | 127 | 14.7 | 116 | 14.6 | 11 | 15.7 | |
Colchicine | 0.683 | ||||||
No | 661 | 76.6 | 606 | 76.4 | 55 | 78.6 | |
Yes | 202 | 23.4 | 187 | 23.6 | 15 | 21.4 | |
Glucocorticoids | 0.247 | ||||||
No | 627 | 72.7 | 572 | 72.1 | 55 | 78.6 | |
Yes | 236 | 27.3 | 221 | 27.9 | 15 | 21.4 | |
NSAIDs | 0.156 | ||||||
No | 628 | 72.8 | 572 | 72.1 | 56 | 80.0 | |
Yes | 235 | 27.2 | 221 | 27.9 | 14 | 20.0 | |
HMG-CoA reductase inhibitor | 0.780 | ||||||
No | 820 | 95.0 | 753 | 95.0 | 67 | 95.7 | |
Yes | 43 | 5.0 | 40 | 5.0 | 3 | 4.3 | |
Angiotensin receptor | 0.424 | ||||||
No | 812 | 94.1 | 744 | 93.8 | 68 | 97.1 | |
Yes | 51 | 5.9 | 49 | 6.2 | 2 | 2.9 | |
Year of diagnosis | 0.904 | ||||||
1995–2000 | 11 | 1.3 | 10 | 1.3 | 1 | 1.4 | |
2001–2005 | 124 | 14.4 | 114 | 14.4 | 10 | 14.3 | |
2006–2010 | 215 | 24.9 | 195 | 24.6 | 20 | 28.6 | |
2011–2015 | 343 | 39.7 | 315 | 39.7 | 28 | 40.0 | |
2016–2018 | 170 | 19.7 | 159 | 20.1 | 11 | 15.7 |
SD: standard deviation; NSAIDs: nonsteroidal anti-inflammatory drugs; HMG-CoA: 3-hydroxy-3-methylglutaryl-CoA.