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. 2018 Nov 12;6:203. doi: 10.1186/s40168-018-0586-1

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Association of BoLA-DRB3.2 polymorphism with interrelationship dynamics of intramammary bacterial communities. Co-occurrence network inference (CoNet) was used to measure the impact of BoLA-DRB3.2 polymorphism on the interrelationship (connectedness) patterns of intramammary bacterial communities during the first week of lactation. The grouped bar charts on the left side of each row show the average proportions of bacterial phyla within the intramammary microbiota of different BoLA-DRB3.2 variants (BstYa and BstYb) at different sampling time points (a day 0, b day 1, c day 6). Stacked bar charts in the middle and on the right side of each row show the total number of connections (significant positive or negative relationships) observed among OTUs belonging to major bacterial phyla within the microbiota of each BoLA-DRB3.2 variant. Color codes have been used to depict the type of relationships; green for positive (co-occurrence) and red for negative (mutual exclusion) relationships