Table 3.
Adjusted1 odds ratio (95% Confidence Interval) of overall, spontaneous, and placental preterm birth (PTB) in association with an interquartile range difference in urinary trace metal concentration and by principal components (PC).
Overall PTB | Spontaneous PTB | Placental PTB | |
Metal | (n cases = 99) (n controls = 291) |
(n cases = 46) (n controls = 291) |
(n cases = 22) (n controls = 291) |
As | 0.98 (0.72, 1.33) | 0.89 (0.58, 1.38) | 1.07 (0.49, 2.35) |
Ba | 1.27 (0.90, 1.77) | 1.27 (0.84, 1.93) | 1.51 (0.75, 3.04) |
Cd | 1.03 (0.78, 1.37) | 1.13 (0.79, 1.63) | 1.73 (0.64, 4.66) |
Cu | 1.41 (1.12, 1.78) | 1.52 (1.14, 2.03) | 1.50 (0.99, 2.27) |
Hg | 1.13 (0.85, 1.51) | 1.28 (0.82, 1.98) | 1.02 (0.70, 1.50) |
Mn | 1.08 (0.85, 1.37) | 1.14 (0.77, 1.69) | 0.97 (0.58, 1.61) |
Mo | 1.05 (0.80, 1.37) | 1.14 (0.71, 1.82) | 0.97 (0.60, 1.58) |
Ni | 0.96 (0.75, 1.22) | 1.19 (0.77, 1.85) | 0.99 (0.71, 1.39) |
Pb | 1.19 (0.91, 1.55) | 1.15 (0.82, 1.60) | 1.45 (0.91, 2.31) |
Se | 1.33 (0.98, 1.81) | 1.69 (1.11, 2.57) | 0.83 (0.53, 1.29) |
Sn | 0.89 (0.65, 1.22) | 0.99 (0.68, 1.43) | 0.83 (0.53, 1.29) |
Tl | 0.96 (0.79, 1.16) | 0.95 (0.64, 1.41) | 0.96 (0.66, 1.42) |
Zn | 1.15 (0.85, 1.57) | 1.21 (0.78, 1.90) | 1.04 (0.50, 2.14) |
Be | 0.48 (0.18, 1.29) | 0.37 (0.09, 1.64) | 0.93 (0.17, 4.98) |
Cr | 1.83 (0.93, 3.61) | 1.39 (0.57, 3.37) | 4.19 (1.16, 15.1) |
U | 1.61 (0.79, 3.27) | 2.05 (0.88, 4.80) | 1.58 (0.36, 6.87) |
W | 1.33 (0.73, 2.42) | 1.94 (0.95, 3.97) | 0.71 (0.16, 3.09) |
Principal Components | |||
Toxic | 1.03 (0.79, 1.34) | 1.02 (0.72, 1.44) | 1.37 (0.80, 2.33) |
Essential | 1.36 (1.05, 1.76) | 1.58 (1.14, 2.20) | 1.16 (0.64, 2.10) |
Fish-related | 1.05 (0.83, 1.35) | 1.09 (0.79, 1.51) | 0.93 (0.59, 1.46) |
Adjusted for specific gravity, maternal age, race, education, pre-pregnancy BMI, gestational age at time of sample collection. Shading denotes metals with >70% of samples below the limit of detection modeled as detect vs. non-detect.