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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Bioorg Med Chem Lett. 2018 Sep 29;28(22):3529–3533. doi: 10.1016/j.bmcl.2018.09.037

Fig. 3.

Fig. 3.

Lung CFU reduction in an acute murine model of TB infection by once-daily oral administration of compound 21b.13 Each dot represents data from 1 mouse. Data were fitted to a sigmoidal curve to estimate ED99 (dose that shows 2 log CFUs reduction compared to untreated mice).