Table IV.
Validation of BMI ≥85th percentile and WFL ≥85th percentile for identifying infants at increased risk for severe obesity (BMI ≥99th percentile) by age 6 years
| Ages | Exceeding threshold, n (%) | Sensitivity, n/N (%) | Specificity, n/N (%) | PPV, n/N (%) | NPV, n/N (%) |
|---|---|---|---|---|---|
| BMI ≥85th percentile | |||||
| 6 mo | 273 (14) | 30/92 (33) | 1643/1886 (87) | 30/273 (11.0) | 1643/1705 (96) |
| 12 mo | 389 (23) | 36/67 (54) | 1248/1601 (78) | 36/389 (9.3) | 1248/1279 (98) |
| 18 mo | 331 (29) | 43/56 (77) | 809/1097 (74) | 43/331 (13) | 809/822 (98) |
| WFL ≥85th percentile | |||||
| 6 mo | 303 (15) | 31/92 (34) | 1607/1879 (86) | 31/303 (10.2) | 1607/1668 (96) |
| 12 mo | 259 (16) | 27/67 (40) | 1354/1586 (85) | 27/259 (10.4) | 1354/1394 (97) |
| 18 mo | 184 (16) | 37/56 (66) | 945/1092 (87) | 37/184 (20.1) | 945/964 (98) |
NPV, negative predictive value; PPV, positive predictive value.
Thresholds applied to the full cohort (n = 2679), BMI≥99th percentile definition of severe obesity applied in young childhood (overall prevalence = 4.5%).