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. 2018 Jul 27;27(6):1607–1617. doi: 10.1007/s10068-018-0441-y

Table 4.

CCD-based optimum conditions of each extraction method for maximum target responses

Extraction methods Target responses
Independent variables Optimum conditions Yield (%) Cinnamic acid (mg/100 mL) Cinnamaldehyde yield (mg/100 mL)
Microwave-assisted extraction (MAE)
X1 Ethanol concentration (%) 59.13 0.90 ± 0.02 6.13 ± 0.08 226.26 ± 1.56
X2 Microwave power (W) 147.59
X3 Extraction time (min) 3.41
Ultrasound-assisted extraction (UAE)
X1 Ethanol concentration (%) 55.34 0.76 ± 0.01 5.67 ± 0.04 205.26 ± 0.03
X2 Extraction time (min) 33.12
Reflux extraction (RE)
X1 Ethanol concentration (%) 63.56 0.94 ± 0.02 6.93 ± 0.21 229.60 ± 0.06
X2 Extraction temperature (°C) 77.62
X3 Extraction time (h) 2.25