Table 4.
Antihypertensive and potential antihypertensive peptides generated by whey fermentation with P. acidilactici SDL1414 after 48 h at 37 °C compared with ACEI peptides reported in literature
| Name | ACEI peptides reported in literature | Present studya | References |
|---|---|---|---|
| αS1-CN | (f14-23) EVLNENLLRF | (f14-23) EVLNENLLRFb (f10–23) GLPQEVLNENLLRF (f10–22) GLPQEVLNENLLR (f10-21) GLPQEVLNENLL |
Torres-Llanez et al. (2011) |
| (f23-34) FFVAPFPEVFGK | (f24-38) FVAPFPEVFGKEKVNEL (f24-34) FVAPFPEVFGK (f25-34) VAPFPEVFGK |
Hayes et al. (2007) | |
| β-CN | (f7-16) NVPGEIVESL (f6-14) LNVPGEIVE (f2-11) ELEELNVPGE |
(f1-27) RELEELNVPGEIVESL (f1-25) RELEELNVPGEIVE (f1-22) RELEELNVPGE (f1-24) RELEELNVPGEIV |
Hayes et al. (2007) and Jin et al. (2016) |
| (f74-97) NIPPLTQTPVVVPPFIQPEVMGVSK | β-CN (f83-95) VVPPFLQPEVMGV | Hayes et al. (2007) | |
| (f191-209) LLYQEPVLGPVRGPFPIIV | (f192-209) LYQEPVLGPVRGPFPIIV (f193-209) YQEPVLGPVRGPFPIIV (f193-208) YQEPVLGPVRGPFPII (f194-209) QEPVLGPVRGPFPIIV (f195-209) EPVLGPVRGPFPIIV |
Jin et al. (2016) | |
| κ-CN | (f161-169) TVQVTSTAV (f64-69) VTSTAV |
(f161-169) TVQVTSTAV (f155-169) SPPEINTVQVTSTAV (f149-169) SPEVIESPPEINTVQVTSTAV (f151-169) EVIESPPEINTVQVTSTAV (f159-169) INTVQVTSTAV (f152-169) VIESPPEINTVQVTSTAV (f150-169) PEVIESPPEINTVQVTSTAV (f157-169) PEINTVQVTSTAV (f151-169) EVIESPPEINTVQVTSTAV |
Tavares et al. (2011) |
| β-lg | (f142-148) ALPMHIR | (f130-149) DEALEKFDKALKALPMHIRL (f130-146) DEALEKFDKALKALPMH (f130-145) DEALEKFDKALKALPM |
Tavares et al. (2011) and Nagpal et al. (2011) |
aPeptides obtained from whey fermentation in the present study. Segments homologous to previously identified ACEI peptides are in bold letters
bPeptide identified in this study which is identical to a previously identified ACEI peptide