Table 3.
Most common extrapulmonary manifestations of PID (adapted from JC Aldave, JFM) [27]
| MOST COMMON EXTRAPULMONARY MANIFESTATIONS OF PID | N (Composition of panel) | Votes in agreement (%) | Degree of agreement |
|---|---|---|---|
| Recurrent or complicated sinusitis | 43 (AI, AP, PI, PP) | 100.0 | Unanimity |
| Recurrent or complicated otitis | 43 (AI, AP, PI, PP) | 93.0 | Consensus |
| Other extrapulmonary infections requiring admission | 43 (AI, AP, PI, PP) | 88.4 | Consensus |
| Ectodermal dysplasia | 43 (AI, AP, PI, PP) | 72.1 | Majority |
| Chronic diarrhea or malabsorption | 43 (AI, AP, PI, PP) | 93.0 | Consensus |
| Difficult-to-treat giardiasis | 43 (AI, AP, PI, PP) | 93.0 | Consensus |
| Autoimmune cytopenias or other autoimmunity | 43 (AI, AP, PI, PP) | 93.0 | Consensus |
| Lymphadenopathies and hepatosplenomegaly | 43 (AI, AP, PI, PP) | 97.7 | Consensus |
| Related cancers, especially associated with viruses | 43 (AI, AP, PI, PP) | 83.7 | Consensus |
| Family history of ID or consistent manifestations | 43 (AI, AP, PI, PP) | 88.4 | Consensus |
| Post-vaccinal infections | 43 (AI, AP, PI, PP) | 79.1 | Majority |
AI: adult immunologists; AP: adult pulmonologists; ID: immunodeficiency; PI: pediatric immunologists; PID: primary immunodeficiency disease; PP: pediatric pulmonologists